This collaborative project investigates Epizootic Shell Disease (ESD) in lobsters, with the goal of evaluating the relative roles of host’s factors and microbial communities in the development of the disease. Our approach focuses on characterizing the composition of the exoskeletal microbial community of healthy and ESD lobsters using molecular tools from microbial ecology while at the same time assessing the status and response of the lobster’s associated immune system.

Antimicrobial compounds produced by lobster hemocytes are revealed here using a green fluorescent dye |

A shell-diseased lobster about to be submitted to blood and shell sampling
We will characterize ESD in lobsters collected from three locations, Eastern Long Island Sound (ELIS) where prevalence is high, Western LIS (WLIS) where prevalence is unexpectedly low, and at a remote reference site (Maine) were prevalence is also low. We will also characterize the temporal progression of ESD development in lobsters collected from ELIS. Through this approach we expect to gain significant insights into the etiology, the development and host responses toward ESD, as well as optimizing tools for the study of crustacean diseases. |